IFIT2 抗体
Quick Overview for IFIT2 抗体 (ABIN7115383)
抗原
See all IFIT2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IFIT2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- interferon-induced protein with tetratricopeptide repeats 2
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亚型
- IgG
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应用备注
- WB: 1:200-1:1000, IHC: 1:50-1:500, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
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别名
- IFIT2
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背景
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Synonyms: Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2)|ISG-54 K|Interferon-induced 54 kDa protein (IFI-54K, P54)|IFIT2|CIG-42|G10P2|IFI54|ISG54
Background: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.
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分子量
- 50-55 kDa
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基因ID
- 3433
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UniProt
- P09913
抗原
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