IRF9 抗体
Quick Overview for IRF9 抗体 (ABIN7115377)
抗原
See all IRF9 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IRF9 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- interferon regulatory factor 9
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亚型
- IgG
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应用备注
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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别名
- IRF9
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背景
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Synonyms: Interferon regulatory factor 9 (IRF-9)|IFN-alpha-responsive transcription factor subunit|ISGF3 p48 subunit|Interferon-stimulated gene factor 3 gamma (ISGF-3 gamma)|Transcriptional regulator ISGF3 subunit gamma|IRF9|ISGF3G
Background: Transcription factor that mediates signaling by type I IFNs(IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases(TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element(ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
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分子量
- 48 kDa
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基因ID
- 10379
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UniProt
- Q00978
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
抗原
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