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IRF9 抗体

This anti-IRF9 antibody is a 兔 多克隆 antibody detecting IRF9 in WB, ELISA, IHC, IF 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7115377
发货至: 中国

Quick Overview for IRF9 抗体 (ABIN7115377)

抗原

See all IRF9 抗体
IRF9 (Interferon Regulatory Factor 9 (IRF9))

适用

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人, 小鼠, 大鼠

宿主

  • 43
  • 7
  • 1

克隆类型

  • 44
  • 6
多克隆

标记

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This IRF9 antibody is un-conjugated

应用范围

  • 38
  • 14
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 原理

    IRF9 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    interferon regulatory factor 9

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    IRF9 (Interferon Regulatory Factor 9 (IRF9))

    别名

    IRF9

    背景

    Synonyms: Interferon regulatory factor 9 (IRF-9)|IFN-alpha-responsive transcription factor subunit|ISGF3 p48 subunit|Interferon-stimulated gene factor 3 gamma (ISGF-3 gamma)|Transcriptional regulator ISGF3 subunit gamma|IRF9|ISGF3G

    Background: Transcription factor that mediates signaling by type I IFNs(IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases(TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element(ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

    分子量

    48 kDa

    基因ID

    10379

    UniProt

    Q00978

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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