INSIG2 抗体
Quick Overview for INSIG2 抗体 (ABIN7115275)
抗原
See all INSIG2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- INSIG2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- insulin induced gene 2
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亚型
- IgG
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anti-Insulin Induced Gene 2 (INSIG2) (AA 50-150) antibody
INSIG2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) antibodyINSIG2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 适用: 人, Cow, 山羊, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 适用: 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, Pig, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- INSIG2 (Insulin Induced Gene 2 (INSIG2))
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别名
- INSIG2
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背景
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Synonyms: Insulin-induced gene 2 protein (INSIG-2)|INSIG2
Background: Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
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分子量
- 30 kDa
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基因ID
- 51141
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UniProt
- Q9Y5U4
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途径
- ER-Nucleus Signaling
抗原
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