IMPA1 抗体
Quick Overview for IMPA1 抗体 (ABIN7115270)
抗原
See all IMPA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IMPA1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- inositol(myo)-1(or 4)-monophosphatase 1
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亚型
- IgG
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anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibody
IMPA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) antibodyIMPA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibodyIMPA1 适用: 人 WB, ELISA, IF, FACS, ICC 宿主: 小鼠 Monoclonal AT2G5 unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibodyIMPA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) antibodyIMPA1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibodyIMPA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6-F11 unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (C-Term) antibodyIMPA1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
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别名
- IMPA1
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背景
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Synonyms: Inositol monophosphatase 1 (IMP 1, IMPase 1)|D-galactose 1-phosphate phosphatase|Inositol-1(or 4)-monophosphatase 1|Lithium-sensitive myo-inositol monophosphatase A1|IMPA1|IMPA
Background: This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1, 4, 5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1, 3-diphosphate, myo-inositol-1, 4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti- manic and anti- depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
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分子量
- 30 kDa
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基因ID
- 3612
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UniProt
- P29218
抗原
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