IVNS1ABP 抗体
Quick Overview for IVNS1ABP 抗体 (ABIN7115224)
抗原
See all IVNS1ABP 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- influenza virus NS1A binding protein
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))
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别名
- IVNS1ABP
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物质类
- Influenza Protein
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背景
- Synonyms:ARA3, FLARA3, KIAA0850, NS1, NS1BP Background:Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization, Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines(By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing, may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
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分子量
- 70 kDa
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基因ID
- 10625
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UniProt
- Q9Y6Y0
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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