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IGKV1-5 抗体

IGKV1-5 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7115198
发货至: 中国
  • 抗原 See all IGKV1-5 products
    IGKV1-5 (Immunoglobulin kappa Variable 1-5 (IGKV1-5))
    适用
    人, 小鼠
    宿主
    • 1
    • 1
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This IGKV1-5 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    immunoglobulin kappa variable 1-5
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    IGKV1-5 (Immunoglobulin kappa Variable 1-5 (IGKV1-5))
    别名
    IGKV1-5 (IGKV1-5 产品)
    别名
    IGKV antibody, IGKV15 antibody, L12 antibody, L12a antibody, V1 antibody, immunoglobulin kappa variable 1-5 antibody, IGKV1-5 antibody
    背景
    Synonyms: Background:V segment of the variable domain of immunoglobulins light chain that participates to the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens(PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen(PubMed:20176268, PubMed:17576170).
    UniProt
    P01602
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