IGKV1-5 抗体
This anti-IGKV1-5 antibody is a 兔 多克隆 antibody detecting IGKV1-5 in WB 和 ELISA. Suitable for 人 和 小鼠.
Quick Overview for IGKV1-5 抗体 (ABIN7115198)
抗原
IGKV1-5
(Immunoglobulin kappa Variable 1-5 (IGKV1-5))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This IGKV1-5 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- immunoglobulin kappa variable 1-5
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亚型
- IgG
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anti-Immunoglobulin kappa Variable 1-5 (IGKV1-5) (AA 1-235) antibody
IGKV1-5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- IGKV1-5 (Immunoglobulin kappa Variable 1-5 (IGKV1-5))
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别名
- IGKV1-5
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背景
- Synonyms: Background:V segment of the variable domain of immunoglobulins light chain that participates to the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens(PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen(PubMed:20176268, PubMed:17576170).
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UniProt
- P01602
抗原
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