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IDS 抗体 (AA 1-300)

This anti-IDS antibody is a 小鼠 单克隆 antibody detecting IDS in WB, IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7115175
发货至: 中国

Quick Overview for IDS 抗体 (AA 1-300) (ABIN7115175)

抗原

See all IDS 抗体
IDS (Iduronate 2-Sulfatase (IDS))

适用

  • 41
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2

宿主

  • 32
  • 10
  • 3
小鼠

克隆类型

  • 38
  • 7
单克隆

标记

  • 30
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IDS antibody is un-conjugated

应用范围

  • 44
  • 17
  • 13
  • 13
  • 11
  • 8
  • 7
  • 6
  • 5
  • 5
  • 3
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

2D2
  • 抗原表位

    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300

    原理

    IDS antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-300aa

    Immunogen: iduronate 2-sulfatase

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    IDS (Iduronate 2-Sulfatase (IDS))

    别名

    IDS

    背景

    Synonyms: Iduronate 2-sulfatase|Alpha-L-iduronate sulfate sulfatase (Idursulfase)|Iduronate 2-sulfatase 42 kDa chain|Iduronate 2-sulfatase 14 kDa chain|IDS|SIDS

    Background: Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).

    分子量

    76 kDa, 55 kDa

    基因ID

    3423

    UniProt

    P22304

    途径

    Glycosaminoglycan Metabolic Process
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