HSD17B6 抗体
Quick Overview for HSD17B6 抗体 (ABIN7115154)
抗原
See all HSD17B6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HSD17B6 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- hydroxysteroid(17-beta) dehydrogenase 6 homolog(Mouse)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))
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别名
- HSD17B6
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背景
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Synonyms: 17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6, 17-beta-HSD6)|3-alpha->beta-hydroxysteroid epimerase (3-alpha->beta-HSE)|Oxidative 3-alpha hydroxysteroid dehydrogenase|Short chain dehydrogenase/reductase family 9C member 6|HSD17B6|RODH|SDR9C6
Background: NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity(in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids(in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone(in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone(in vitro). Has retinol dehydrogenase activity towards all-trans-retinol(in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
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分子量
- 33-35 kDa
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基因ID
- 8630
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UniProt
- O14756
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途径
- Steroid Hormone Biosynthesis
抗原
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