HSD17B11 抗体 (AA 28-300)
Quick Overview for HSD17B11 抗体 (AA 28-300) (ABIN7115150)
抗原
See all HSD17B11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 28-300
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原理
- HSD17B11 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 28-300aa
Immunogen: hydroxysteroid(17-beta) dehydrogenase 11
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亚型
- IgG
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应用备注
- WB: 1:500-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
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别名
- HSD17B11
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背景
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Synonyms: Estradiol 17-beta-dehydrogenase 11|17-beta-hydroxysteroid dehydrogenase 11 (17-beta-HSD 11, 17bHSD11, 17betaHSD11)|17-beta-hydroxysteroid dehydrogenase XI (17-beta-HSD XI, 17betaHSDXI)|Cutaneous T-cell lymphoma-associated antigen HD-CL-03 (CTCL-associated antigen HD-CL-03)|Dehydrogenase/reductase SDR family member 8|Retinal short-chain dehydrogenase/reductase 2 (retSDR2)|Short chain dehydrogenase/reductase family 16C member 2|HSD17B11|DHRS8|PAN1B|SDR16C2
Background: Can convert androstan-3-alpha,17-beta-diol(3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA(dehydroepiandrosterone), or A-dione(4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
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分子量
- 33 kDa
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基因ID
- 51170
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UniProt
- Q8NBQ5
抗原
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