HSD17B10 抗体 (AA 1-261)
Quick Overview for HSD17B10 抗体 (AA 1-261) (ABIN7115148)
抗原
See all HSD17B10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-261
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原理
- HSD17B10 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-261aa
Immunogen: hydroxysteroid(17-beta) dehydrogenase 10
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亚型
- IgG1
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) antibody
HSD17B10 适用: 人, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 5E2 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (C-Term) antibodyHSD17B10 适用: 人 WB, IF, IHC (p), ICC, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 48-261) antibodyHSD17B10 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 48-261) antibodyHSD17B10 适用: 人, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 140-172) antibodyHSD17B10 适用: 人, 小鼠, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB56913 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) antibodyHSD17B10 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 1-261) antibodyHSD17B10 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 14-48) antibodyHSD17B10 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB56756 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 1-261) antibodyHSD17B10 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (C-Term) antibodyVerified HSD17B10 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
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别名
- HSD17B10
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背景
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Synonyms: 3-hydroxyacyl-CoA dehydrogenase type-2|17-beta-estradiol 17-dehydrogenase|2-methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD)|3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))|3-hydroxy-2-methylbutyryl-CoA dehydrogenase|3-hydroxyacyl-CoA dehydrogenase type II|3alpha(or 20beta)-hydroxysteroid dehydrogenase|7-alpha-hydroxysteroid dehydrogenase|Endoplasmic reticulum-associated amyloid beta-peptide-binding protein|Mitochondrial ribonuclease P protein 2 (Mitochondrial RNase P protein 2)|Short chain dehydrogenase/reductase family 5C member 1|Short-chain type dehydrogenase/reductase XH98G2|Type II HADH|HSD17B10|ERAB|HADH2|MRPP2|SCHAD|SDR5C1|XH98G2
Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease(AD).
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分子量
- 27 kDa
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基因ID
- 3028
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UniProt
- Q99714
抗原
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