HSD3B7 抗体
Quick Overview for HSD3B7 抗体 (ABIN7115138)
抗原
See all HSD3B7 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HSD3B7 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 7
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
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别名
- HSD3B7
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背景
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Synonyms: 3 beta-hydroxysteroid dehydrogenase type 7|3 beta-hydroxysteroid dehydrogenase type VII (3-beta-HSD VII)|3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase (C(27) 3-beta-HSD)|Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase|HSD3B7
Background: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis(PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.
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分子量
- 36 kDa
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基因ID
- 80270
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UniProt
- Q9H2F3
抗原
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