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HOMER1 抗体

This anti-HOMER1 antibody is a 兔 多克隆 antibody detecting HOMER1 in WB, ELISA, IHC, IP 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN7115100
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HOMER1 抗体 (ABIN7115100)

抗原

See all HOMER1 抗体
HOMER1 (Homer Homolog 1 (HOMER1))

适用

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人, 小鼠

宿主

  • 47
  • 13
  • 1

克隆类型

  • 39
  • 22
多克隆

标记

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This HOMER1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 原理

    HOMER1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    homer homolog 1(Drosophila)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    HOMER1 (Homer Homolog 1 (HOMER1))

    别名

    HOMER1

    背景

    Synonyms: Homer protein homolog 1 (Homer-1)|HOMER1|SYN47

    Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.

    分子量

    46-48 kDa

    基因ID

    9456

    UniProt

    Q86YM7

    途径

    Skeletal Muscle Fiber Development
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