HARS2 抗体
Quick Overview for HARS2 抗体 (ABIN7115030)
抗原
See all HARS2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HARS2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- histidyl-tRNA synthetase 2, mitochondrial (putative)
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HARS2 (Histidyl-tRNA Synthetase 2, Mitochondrial (Putative) (HARS2))
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别名
- HARS2
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背景
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Synonyms: Histidine--tRNA ligase, mitochondrial|Histidine--tRNA ligase-like|Histidyl-tRNA synthetase (HisRS)|HARS2|HARSL|HARSR|HO3
Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.
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分子量
- 50 kDa
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基因ID
- 23438
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UniProt
- P49590
抗原
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