HNMT 抗体
Quick Overview for HNMT 抗体 (ABIN7115023)
抗原
See all HNMT 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HNMT antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- histamine N-methyltransferase
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP : 1:20 - 1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HNMT (Histamine N-Methyltransferase (HNMT))
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别名
- HNMT
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背景
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Synonyms: Histamine N-methyltransferase (HMT)|HNMT
Background: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
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分子量
- 27 kDa
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基因ID
- 3176
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UniProt
- P50135
抗原
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