HNRNPC 抗体
Quick Overview for HNRNPC 抗体 (ABIN7114978)
抗原
See all HNRNPC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- HNRNPC antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- heterogeneous nuclear ribonucleoprotein C(C1/C2)
-
亚型
- IgG
-
-
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody
KO Validated HNRNPC 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC 适用: 人 WB, IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 9G1 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (pSer260) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-250) antibodyHNRNPC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人, 兔, Cow, 犬, Pig, 猴, 马, 山羊, 豚鼠, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 241-290) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (Middle Region) antibodyHNRNPC 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 马, 斑马鱼, 山羊, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-142), (N-Term) antibodyHNRNPC 适用: 人, 大鼠, 小鼠, 兔, Cow WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
-
别名
- HNRNPC
-
背景
-
Synonyms: Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)|HNRNPC|HNRPC
Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles(PubMed:8264621). Specifically recognizes and binds N6-methyladenosine(m6A)-containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non-coding RNAs(lncRNAs) via a mechanism named 'm(6)A-switch' to facilitate binding of HNRNPC, leading to regulation of mRNA splicing(PubMed:25719671). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules(PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621).
-
分子量
- 32 kDa
-
基因ID
- 3183
-
UniProt
- P07910
抗原
-
