HNRNPC 抗体
Quick Overview for HNRNPC 抗体 (ABIN7114978)
抗原
See all HNRNPC 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HNRNPC antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- heterogeneous nuclear ribonucleoprotein C(C1/C2)
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亚型
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody
KO Validated HNRNPC 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC 适用: 人 WB, IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 9G1 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (pSer260) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-250) antibodyHNRNPC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人, 兔, Cow, 犬, Pig, 猴, 马, 山羊, 豚鼠, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 241-290) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-142), (N-Term) antibodyHNRNPC 适用: 人, 大鼠, 小鼠, 兔, Cow WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
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别名
- HNRNPC
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背景
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Synonyms: Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)|HNRNPC|HNRPC
Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles(PubMed:8264621). Specifically recognizes and binds N6-methyladenosine(m6A)-containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non-coding RNAs(lncRNAs) via a mechanism named 'm(6)A-switch' to facilitate binding of HNRNPC, leading to regulation of mRNA splicing(PubMed:25719671). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules(PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621).
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分子量
- 32 kDa
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基因ID
- 3183
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UniProt
- P07910
抗原
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