GRB7 抗体
Quick Overview for GRB7 抗体 (ABIN7114786)
抗原
See all GRB7 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GRB7 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- growth factor receptor-bound protein 7
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亚型
- IgG
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anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 298-489) antibody
GRB7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 1-532) antibodyGRB7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 1-532) antibodyGRB7 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 66-327) antibodyGRB7 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 37-136) antibodyGRB7 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 233-532) antibodyGRB7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) antibodyGRB7 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (AA 124-141), (Middle Region) antibodyGRB7 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (N-Term) antibodyGRB7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 7 (GRB7) (N-Term) antibodyVerified GRB7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
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别名
- GRB7
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背景
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Synonyms: Growth factor receptor-bound protein 7|B47|Epidermal growth factor receptor GRB-7|GRB7 adapter protein|GRB7
Background: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress(By similarity).
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分子量
- 60-70 kDa
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基因ID
- 2886
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UniProt
- Q14451
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途径
- EGFR Signaling Pathway, Ribonucleoprotein Complex Subunit Organization
抗原
-
