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GRB7 抗体

GRB7 适用: 人, 小鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7114786
发货至: 中国
  • 抗原 See all GRB7 抗体
    GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
    适用
    • 51
    • 15
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 48
    • 3
    • 1
    • 1
    克隆类型
    • 51
    • 2
    多克隆
    标记
    • 28
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRB7 antibody is un-conjugated
    应用范围
    • 29
    • 21
    • 12
    • 12
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    growth factor receptor-bound protein 7
    亚型
    IgG
    Top Product
    Discover our top product GRB7 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
    别名
    GRB7 (GRB7 产品)
    背景
    Synonyms: Background:Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress(By similarity).
    分子量
    60-70 kDa
    基因ID
    2886
    UniProt
    Q14451
    途径
    EGFR Signaling Pathway, Ribonucleoprotein Complex Subunit Organization
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