GADD45GIP1 抗体
Quick Overview for GADD45GIP1 抗体 (ABIN7114772)
抗原
See all GADD45GIP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GADD45GIP1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- growth arrest and DNA-damage-inducible, gamma interacting protein 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
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别名
- GADD45GIP1
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背景
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Synonyms: Large ribosomal subunit protein mL64|39S ribosomal protein L59, mitochondrial (MRP-L59)|CKII beta-associating protein|CR6-interacting factor 1 (CRIF1)|Growth arrest and DNA damage-inducible proteins-interacting protein 1|Papillomavirus L2-interacting nuclear protein 1 (PLINP, PLINP-1)|p53-responsive gene 6 protein|GADD45GIP1|MRPL59|PLINP1|PRG6
Background: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
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分子量
- 25-28 kDa
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基因ID
- 90480
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UniProt
- Q8TAE8
抗原
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