GLYR1 抗体
Quick Overview for GLYR1 抗体 (ABIN7114720)
抗原
See all GLYR1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GLYR1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- cytokine-like nuclear factor n-pac
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))
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别名
- GLYR1
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背景
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Synonyms: Cytokine-like nuclear factor N-PAC (NPAC)|3-hydroxyisobutyrate dehydrogenase-like protein|Glyoxylate reductase 1 homolog|Nuclear protein NP60|Nuclear protein of 60 kDa|Nucleosome-destabilizing factor (hNDF)|Putative oxidoreductase GLYR1|GLYR1|HIBDL|NDF|NP60|NPAC
Background: May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3(H3K36me3).
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分子量
- 60 kDa
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基因ID
- 84656
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UniProt
- Q49A26
抗原
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