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Glutathione Peroxidase 2 抗体

This anti-Glutathione Peroxidase 2 antibody is a 兔 多克隆 antibody detecting Glutathione Peroxidase 2 in ELISA, WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114637
发货至: 中国

Quick Overview for Glutathione Peroxidase 2 抗体 (ABIN7114637)

抗原

See all Glutathione Peroxidase 2 (GPX2) 抗体
Glutathione Peroxidase 2 (GPX2)

适用

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人, 小鼠, 大鼠

宿主

  • 15
  • 1
  • 1

克隆类型

  • 15
  • 2
多克隆

标记

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  • 2
  • 1
  • 1
This Glutathione Peroxidase 2 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Glutathione peroxidase 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Glutathione Peroxidase 2 (GPX2)

    别名

    GPX2

    背景

    Synonyms:GPX2, GI-GPx, GPRP, GPRP-2 Background:The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.

    分子量

    21 kDa

    UniProt

    P18283

    途径

    Thyroid Hormone Synthesis
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