GEMIN5 抗体
This anti-GEMIN5 antibody is a 兔 多克隆 antibody detecting GEMIN5 in WB, IP, ELISA, IHC 和 IF. Suitable for 人.
Quick Overview for GEMIN5 抗体 (ABIN7114527)
抗原
See all GEMIN5 抗体
GEMIN5
(Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
适用
人
宿主
兔
克隆类型
多克隆
标记
This GEMIN5 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- gem(nuclear organelle) associated protein 5
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亚型
- IgG
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anti-Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5) (AA 750-950) antibody
GEMIN5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
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别名
- GEMIN5
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背景
- Synonyms: Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. GEMIN5 acts as the snRNA-binding protein of the SMN complex.
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分子量
- 168 kDa
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基因ID
- 25929
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UniProt
- Q8TEQ6
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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