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GSDMD 抗体

This anti-GSDMD antibody is a 兔 多克隆 antibody detecting GSDMD in WB, ELISA, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114492
发货至: 中国

Quick Overview for GSDMD 抗体 (ABIN7114492)

抗原

See all GSDMD 抗体
GSDMD (Gasdermin D (GSDMD))

适用

人, 小鼠, 大鼠

宿主

  • 23
  • 6
  • 1

克隆类型

  • 23
  • 7
多克隆

标记

  • 26
  • 2
  • 1
  • 1
This GSDMD antibody is un-conjugated

应用范围

  • 25
  • 11
  • 10
  • 8
  • 7
  • 7
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    gasdermin D

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    GSDMD (Gasdermin D (GSDMD))

    别名

    GSDMD

    背景

    Synonyms:DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1 Background:GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

    分子量

    50-53 kDa

    基因ID

    79792

    UniProt

    P57764

    途径

    Inflammasome
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