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GSDMD 抗体 (AA 276-484)

This 兔 多克隆 anti-GSDMD antibody specifically detects GSDMD in WB, ELISA, IF 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7114492
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GSDMD 抗体 (AA 276-484) (ABIN7114492)

抗原

See all GSDMD 抗体
GSDMD (Gasdermin D (GSDMD))

适用

人, 小鼠, 大鼠

宿主

  • 23
  • 11
  • 1

克隆类型

  • 22
  • 13
多克隆

标记

  • 28
  • 3
  • 1
  • 1
  • 1
  • 1
This GSDMD antibody is un-conjugated

应用范围

  • 28
  • 12
  • 11
  • 10
  • 7
  • 7
  • 5
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
  • 抗原表位

    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 276-484

    原理

    GSDMD antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 276-484aa

    Immunogen: gasdermin D

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    GSDMD (Gasdermin D (GSDMD))

    别名

    GSDMD

    背景

    Synonyms: Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D, C-terminal (GSDMD-CT, hGSDMD-CTD)|Gasdermin-D, p13|Gasdermin-D, 13 kDa (13 kDa GSDMD)|Gasdermin-D, p40|GSDMD|DFNA5L|GSDMDC1

    Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

    分子量

    50-53 kDa

    基因ID

    79792

    UniProt

    P57764

    途径

    Inflammasome
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