GSDMD 抗体 (AA 276-484)
Quick Overview for GSDMD 抗体 (AA 276-484) (ABIN7114492)
抗原
See all GSDMD 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 276-484
-
原理
- GSDMD antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
-
Immunogen sequence: 276-484aa
Immunogen: gasdermin D
-
亚型
- IgG
-
-
anti-Gasdermin D (GSDMD) (AA 1-484) antibody
GSDMD 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F12-1B2 unconjugated
anti-Gasdermin D (GSDMD) (AA 276-484) antibodyGSDMD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) antibodyGSDMD 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-485) antibodyGSDMD 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3F12-1B2 unconjugated
anti-Gasdermin D (GSDMD) antibodyGSDMD 适用: 人 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-326) antibodyGSDMD 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-256) antibodyGSDMD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 232-484) antibodyGSDMD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-484) antibodyGSDMD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gasdermin D (GSDMD) (AA 1-484) antibodyGSDMD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- GSDMD (Gasdermin D (GSDMD))
-
别名
- GSDMD
-
背景
-
Synonyms: Gasdermin-D|Gasdermin domain-containing protein 1|Gasdermin-D, C-terminal (GSDMD-CT, hGSDMD-CTD)|Gasdermin-D, p13|Gasdermin-D, 13 kDa (13 kDa GSDMD)|Gasdermin-D, p40|GSDMD|DFNA5L|GSDMDC1
Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
-
分子量
- 50-53 kDa
-
基因ID
- 79792
-
UniProt
- P57764
-
途径
- Inflammasome
抗原
-
