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GPR161 抗体

This anti-GPR161 antibody is a 兔 多克隆 antibody detecting GPR161 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114407
发货至: 中国

Quick Overview for GPR161 抗体 (ABIN7114407)

抗原

See all GPR161 抗体
GPR161 (G Protein-Coupled Receptor 161 (GPR161))

适用

  • 47
  • 10
  • 7
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  • 6
  • 6
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  • 5
  • 5
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 45
  • 2

克隆类型

  • 45
  • 2
多克隆

标记

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  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This GPR161 antibody is un-conjugated

应用范围

  • 34
  • 14
  • 13
  • 13
  • 12
  • 9
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    G protein-coupled receptor 161

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    GPR161 (G Protein-Coupled Receptor 161 (GPR161))

    别名

    GPR161

    背景

    Synonyms: Background:Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown(By similarity).

    分子量

    70 kDa

    基因ID

    23432

    UniProt

    Q8N6U8

    途径

    cAMP Metabolic Process
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