Fibromodulin 抗体
Quick Overview for Fibromodulin 抗体 (ABIN7114223)
抗原
See all Fibromodulin (FMOD) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- FMOD antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- fibromodulin
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Fibromodulin (FMOD)
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别名
- FMOD
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背景
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Synonyms: Fibromodulin (FM)|Collagen-binding 59 kDa protein|Keratan sulfate proteoglycan fibromodulin (KSPG fibromodulin)|FMOD|FM|SLRR2E
Background: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
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分子量
- 45 kDa
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基因ID
- 2331
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UniProt
- Q06828
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途径
- Glycosaminoglycan Metabolic Process
抗原
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