FERMT3 抗体
Quick Overview for FERMT3 抗体 (ABIN7114179)
抗原
See all FERMT3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- FERMT3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- fermitin family homolog 3(Drosophila)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- FERMT3 (Fermitin Family Member 3 (FERMT3))
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别名
- FERMT3
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背景
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Synonyms: Fermitin family homolog 3|Kindlin-3|MIG2-like protein|Unc-112-related protein 2|FERMT3|KIND3|MIG2B|URP2
Background: Plays a central role in cell adhesion in hematopoietic cells(PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3(ITGB1, ITGB2 and ITGB3)(By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells(PubMed:19234460). Required for activation of integrin beta-2(ITGB2) in polymorphonuclear granulocytes(PMNs)(By similarity). Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.
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分子量
- 72-76 kDa
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基因ID
- 83706
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UniProt
- Q86UX7
抗原
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