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FER 抗体

This anti-FER antibody is a 兔 多克隆 antibody detecting FER in WB, ELISA, IHC, IF 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN7114175
发货至: 中国

Quick Overview for FER 抗体 (ABIN7114175)

抗原

See all FER 抗体
FER (FER Tyrosine Kinase (FER))

适用

  • 70
  • 60
  • 17
  • 6
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  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 83
  • 10

克隆类型

  • 83
  • 10
多克隆

标记

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  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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This FER antibody is un-conjugated

应用范围

  • 78
  • 32
  • 26
  • 26
  • 14
  • 13
  • 11
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    FER antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    fer(fps/fes related) tyrosine kinase

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    FER (FER Tyrosine Kinase (FER))

    别名

    FER

    背景

    Synonyms: Tyrosine-protein kinase Fer|Feline encephalitis virus-related kinase FER|Fujinami poultry sarcoma/Feline sarcoma-related protein Fer|Proto-oncogene c-Fer|Tyrosine kinase 3|p94-Fer|FER|TYK3

    Background: Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide(LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.

    分子量

    95 kDa

    基因ID

    2241

    UniProt

    P16591
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