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SUPT16H 抗体

This anti-SUPT16H antibody is a 兔 多克隆 antibody detecting SUPT16H in ELISA, WB, IHC 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7114058
发货至: 中国

Quick Overview for SUPT16H 抗体 (ABIN7114058)

抗原

See all SUPT16H 抗体
SUPT16H (FACT complex subunit SPT16 (SUPT16H))

适用

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人, 小鼠

宿主

  • 42
  • 5
  • 1

克隆类型

  • 43
  • 5
多克隆

标记

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This SUPT16H antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    suppressor of Ty 16 homolog(S. cerevisiae)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    SUPT16H (FACT complex subunit SPT16 (SUPT16H))

    别名

    SUPT16H

    背景

    Synonyms:FACT140, FACTP140 Background:Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2(casein kinase II).

    分子量

    140 kDa

    基因ID

    6830

    UniProt

    Q9Y5B9

    途径

    Chromatin Binding
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