FBXO7 抗体
Quick Overview for FBXO7 抗体 (ABIN7114054)
抗原
See all FBXO7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- FBXO7 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- F-box protein 7
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- FBXO7 (F-Box Protein 7 (FBXO7))
-
别名
- FBXO7
-
背景
-
Synonyms: F-box only protein 7|FBXO7|FBX7
Background: Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
-
分子量
- 58.5 kDa
-
基因ID
- 25793
-
UniProt
- Q9Y3I1
抗原
-