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F-Box Protein 3 抗体

This anti-F-Box Protein 3 antibody is a 兔 多克隆 antibody detecting F-Box Protein 3 in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114048
发货至: 中国

Quick Overview for F-Box Protein 3 抗体 (ABIN7114048)

抗原

See all F-Box Protein 3 (FBXO3) 抗体
F-Box Protein 3 (FBXO3)

适用

  • 29
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 27
  • 2

克隆类型

  • 29
多克隆

标记

  • 15
  • 4
  • 3
  • 3
  • 2
  • 2
This F-Box Protein 3 antibody is un-conjugated

应用范围

  • 22
  • 18
  • 12
  • 5
  • 2
  • 1
  • 1
ELISA, Western Blotting (WB)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    F-box protein 3

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    F-Box Protein 3 (FBXO3)

    别名

    FBXO3

    背景

    Synonyms:FBX3 Background:Substrate recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

    分子量

    48-50kd

    基因ID

    26273

    UniProt

    Q9UK99
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