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FBXO2 抗体

This anti-FBXO2 antibody is a 兔 多克隆 antibody detecting FBXO2 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114045
发货至: 中国

Quick Overview for FBXO2 抗体 (ABIN7114045)

抗原

See all FBXO2 抗体
FBXO2 (F-Box Protein 2 (FBXO2))

适用

  • 28
  • 22
  • 4
  • 3
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 33
  • 4

克隆类型

  • 35
  • 2
多克隆

标记

  • 18
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FBXO2 antibody is un-conjugated

应用范围

  • 36
  • 13
  • 13
  • 13
  • 10
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    F-box protein 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    FBXO2 (F-Box Protein 2 (FBXO2))

    别名

    FBXO2

    背景

    Synonyms:FBX2 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway(ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type(By similarity).

    分子量

    33-40 kDa

    基因ID

    26232

    UniProt

    Q9UK22
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