EYA4
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 647
应用备注
WB: 1:500-1:2000, IF: 1:20-1:200
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
抗原
EYA4
(Eyes Absent Homolog 4 (EYA4))
别名
EYA4
背景
Synonyms: Background:Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX(H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye(By similarity).