EYA4 抗体
Quick Overview for EYA4 抗体 (ABIN7114031)
抗原
See all EYA4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EYA4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- eyes absent homolog 4(Drosophila)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EYA4 (Eyes Absent Homolog 4 (EYA4))
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别名
- EYA4
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背景
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Synonyms: Eyes absent homolog 4|EYA4
Background: Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX(H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye(By similarity).
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分子量
- 67 kDa
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基因ID
- 2070
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UniProt
- O95677
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途径
- Sensory Perception of Sound
抗原
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