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ERI1 抗体

This anti-ERI1 antibody is a 兔 多克隆 antibody detecting ERI1 in WB, ELISA, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7114005
发货至: 中国

Quick Overview for ERI1 抗体 (ABIN7114005)

抗原

See all ERI1 抗体
ERI1 (Exoribonuclease 1 (ERI1))

适用

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  • 35
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  • 5
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  • 2
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  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 58
  • 2

克隆类型

  • 58
  • 2
多克隆

标记

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  • 4
  • 4
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ERI1 antibody is un-conjugated

应用范围

  • 34
  • 22
  • 13
  • 13
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  • 8
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  • 3
  • 3
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    exoribonuclease 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    ERI1 (Exoribonuclease 1 (ERI1))

    别名

    ERI1

    背景

    Synonyms:3'EXO, THEX1 Background:RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs(siRNAs) in vitro, suggesting a possible role as regulator of RNA interference(RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

    分子量

    46kd

    基因ID

    90459

    UniProt

    Q8IV48
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