EXD2 抗体 (AA 400-621)
Quick Overview for EXD2 抗体 (AA 400-621) (ABIN7114003)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-621
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原理
- EXD2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 400-621aa
Immunogen: exonuclease 3'-5' domain containing 2
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
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别名
- EXD2
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背景
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Synonyms: Exonuclease 3'-5' domain-containing protein 2|3'-5' exoribonuclease EXD2|Exonuclease 3'-5' domain-like-containing protein 2|EXD2|C14orf114|EXDL2
Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
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分子量
- 56 kDa
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基因ID
- 55218
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UniProt
- Q9NVH0
抗原
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