EXD1 抗体
Quick Overview for EXD1 抗体 (ABIN7114002)
抗原
See all EXD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EXD1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- exonuclease 3'-5' domain containing 1
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亚型
- IgG
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应用备注
- WB: 1:200-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EXD1 (Exonuclease 3'-5' Domain Containing 1 (EXD1))
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别名
- EXD1
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背景
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Synonyms: piRNA biogenesis protein EXD1|Exonuclease 3'-5' domain-containing protein 1|Exonuclease 3'-5' domain-like-containing protein 1|Inactive exonuclease EXD1|EXD1|EXDL1
Background: RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity(By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease(By similarity).
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分子量
- 36 kDa
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基因ID
- 161829
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UniProt
- Q8NHP7
抗原
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