EXD1 抗体
This anti-EXD1 antibody is a 兔 多克隆 antibody detecting EXD1 in WB, IF, ELISA 和 IHC. Suitable for 人, 大鼠 和 小鼠.
Quick Overview for EXD1 抗体 (ABIN7114002)
抗原
See all EXD1 抗体
EXD1
(Exonuclease 3'-5' Domain Containing 1 (EXD1))
适用
人, 大鼠, 小鼠
宿主
兔
克隆类型
多克隆
标记
This EXD1 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- exonuclease 3'-5' domain containing 1
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亚型
- IgG
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应用备注
- WB: 1:200-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- EXD1 (Exonuclease 3'-5' Domain Containing 1 (EXD1))
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别名
- EXD1
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背景
- Synonyms:EXDL1 Background:RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity(By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease(By similarity).
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分子量
- 36 kDa
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基因ID
- 161829
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UniProt
- Q8NHP7
抗原
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