eIF4EBP2 抗体
Quick Overview for eIF4EBP2 抗体 (ABIN7113973)
抗原
See all eIF4EBP2 (EIF4EBP2) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EIF4EBP2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- eukaryotic translation initiation factor 4E binding protein 2
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 1-120) antibody
EIF4EBP2 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) antibodyEIF4EBP2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (N-Term) antibodyEIF4EBP2 适用: 人, 小鼠, Cow, 犬, Pig, 大鼠, 山羊, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 1-120) antibodyEIF4EBP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 61-120) antibodyEIF4EBP2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 87-115) antibodyEIF4EBP2 适用: 人 IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 61-120) antibodyEIF4EBP2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 7-56) antibodyEIF4EBP2 适用: 人, 小鼠, Cow, 犬, Pig, 大鼠, 山羊, 兔, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 87-115), (C-Term) antibodyEIF4EBP2 适用: 人 WB 宿主: 兔 Polyclonal RB41859 unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))
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别名
- EIF4EBP2
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背景
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Synonyms: Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2, eIF4E-binding protein 2)|EIF4EBP2
Background: Repressor of translation initiation involved in synaptic plasticity, learning and memory formation(By similarity). Regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation(PubMed:25533957). EIF4EBP2 is enriched in brain and acts as a regulator of synapse activity and neuronal stem cell renewal via its ability to repress translation initiation(By similarity). Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways(By similarity).
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分子量
- ~20 kDa
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基因ID
- 1979
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UniProt
- Q13542
抗原
-
