ERLIN1 抗体
Quick Overview for ERLIN1 抗体 (ABIN7113870)
抗原
See all ERLIN1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ERLIN1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ER lipid raft associated 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))
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别名
- ERLIN1
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背景
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Synonyms: Erlin-1|Endoplasmic reticulum lipid raft-associated protein 1|Protein KE04|Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 (SPFH domain-containing protein 1)|ERLIN1|C10orf69|KE04|KEO4|SPFH1
Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex(PubMed:24217618).
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分子量
- 39 kDa
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基因ID
- 10613
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UniProt
- O75477
抗原
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