ELL 抗体
Quick Overview for ELL 抗体 (ABIN7113778)
抗原
See all ELL 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- ELL antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- elongation factor RNA polymerase II
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- ELL (Elongation Factor RNA Polymerase II (ELL))
-
别名
- ELL
-
背景
-
Synonyms: RNA polymerase II elongation factor ELL|Eleven-nineteen lysine-rich leukemia protein|ELL|C19orf17
Background: Elongation factor component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II-and III-dependent snRNA gene transcription(PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.
-
分子量
- 68-80 kDa
-
基因ID
- 8178
-
UniProt
- P55199
抗原
-