ELK4 抗体
Quick Overview for ELK4 抗体 (ABIN7113769)
抗原
See all ELK4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ELK4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ELK4, ETS-domain protein(SRF accessory protein 1)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ELK4 (ELK4, ETS-Domain Protein (SRF Accessory Protein 1) (ELK4))
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别名
- ELK4
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背景
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Synonyms: ETS domain-containing protein Elk-4|Serum response factor accessory protein 1 (SAP-1, SRF accessory protein 1)|ELK4|SAP1
Background: Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18'(H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor(SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.
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分子量
- 47 kDa
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基因ID
- 2005
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UniProt
- P28324
抗原
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