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EHD3 抗体

EHD3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7113755
发货至: 中国
  • 抗原 See all EHD3 抗体
    EHD3 (EH-Domain Containing 3 (EHD3))
    适用
    • 25
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 22
    • 3
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EHD3 antibody is un-conjugated
    应用范围
    • 14
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    EH-domain containing 3
    亚型
    IgG
    Top Product
    Discover our top product EHD3 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    EHD3 (EH-Domain Containing 3 (EHD3))
    别名
    EHD3 (EHD3 产品)
    别名
    PAST3 antibody, Ehd2 antibody, EHD3 antibody, si:ch211-147c1.2 antibody, MGC146452 antibody, EH domain containing 3 antibody, EH-domain containing 3 antibody, EH domain containing 3 L homeolog antibody, EHD3 antibody, Ehd3 antibody, ehd3 antibody, ehd3.L antibody
    背景
    Synonyms:EHD2, Background:ATP-and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis(PubMed:25686250). In vitro causes tubulation of endocytic membranes(PubMed:24019528). Binding to phosphatidic acid induces its membrane tubulation activity(By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment(ERC), retrograde early endosome to Golgi, and endosome to plasma membrane(rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology(PubMed:16251358, PubMed:17233914, PubMed:19139087, PubMed:23781025). Involved in the recycling of internalized D1 dopamine receptor(PubMed:21791287). Plays a role in cardiac protein trafficking probably implicating ANK2(PubMed:20489164). Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction(By similarity). In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function(By similarity). Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance(PubMed:23781025). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing(By similarity). Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis, possibly sharing redundant functions with EHD1(PubMed:25686250).
    分子量
    61 kDa
    基因ID
    30845
    UniProt
    Q9NZN3
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