EHD3 抗体
Quick Overview for EHD3 抗体 (ABIN7113755)
抗原
See all EHD3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EHD3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- EH-domain containing 3
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亚型
- IgG
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anti-EH-Domain Containing 3 (EHD3) (AA 357-406) antibody
EHD3 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 4B7 unconjugated
anti-EH-Domain Containing 3 (EHD3) (AA 357-406) antibodyEHD3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-EH-Domain Containing 3 (EHD3) (AA 269-498) antibodyEHD3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EH-Domain Containing 3 (EHD3) (AA 22-48), (N-Term) antibodyEHD3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17956 unconjugated
anti-EH-Domain Containing 3 (EHD3) (AA 189-216) antibodyEHD3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17957 unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EHD3 (EH-Domain Containing 3 (EHD3))
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别名
- EHD3
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背景
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Synonyms: EH domain-containing protein 3|PAST homolog 3|EHD3|EHD2|PAST3
Background: ATP-and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis(PubMed:25686250). In vitro causes tubulation of endocytic membranes(PubMed:24019528). Binding to phosphatidic acid induces its membrane tubulation activity(By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment(ERC), retrograde early endosome to Golgi, and endosome to plasma membrane(rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology(PubMed:16251358, PubMed:17233914, PubMed:19139087, PubMed:23781025). Involved in the recycling of internalized D1 dopamine receptor(PubMed:21791287). Plays a role in cardiac protein trafficking probably implicating ANK2(PubMed:20489164). Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction(By similarity). In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function(By similarity). Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance(PubMed:23781025). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing(By similarity). Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis, possibly sharing redundant functions with EHD1(PubMed:25686250).
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分子量
- 61 kDa
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基因ID
- 30845
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UniProt
- Q9NZN3
抗原
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