电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

EHD1 抗体

This anti-EHD1 antibody is a 兔 多克隆 antibody detecting EHD1 in WB, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7113753
发货至: 中国

Quick Overview for EHD1 抗体 (ABIN7113753)

抗原

See all EHD1 抗体
EHD1 (EH-Domain Containing 1 (EHD1))

适用

  • 28
  • 12
  • 10
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 27
  • 1

克隆类型

  • 26
  • 2
多克隆

标记

  • 17
  • 4
  • 3
  • 2
  • 1
  • 1
This EHD1 antibody is un-conjugated

应用范围

  • 24
  • 19
  • 9
  • 5
  • 4
  • 4
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    EH-domain containing 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    EHD1 (EH-Domain Containing 1 (EHD1))

    别名

    EHD1

    背景

    Synonyms:PAST, Background:ATP-and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes(PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes(PubMed:15020713, PubMed:17233914, PubMed:20801876). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth(By similarity). Plays a role in myoblast fusion(By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing(By similarity). Plays a role in the formation of the ciliary vesicle(CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles(DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis(PubMed:25686250).

    分子量

    61 kDa

    基因ID

    10938

    UniProt

    Q9H4M9

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
You are here:
Chat with us!