ECD/SGT1 抗体 (AA 1-130)
Quick Overview for ECD/SGT1 抗体 (AA 1-130) (ABIN7113709)
抗原
See all ECD/SGT1 (ECD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-130
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原理
- ECD antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-130aa
Immunogen: ecdysoneless homolog(Drosophila)
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亚型
- IgG
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anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibody
ECD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-300) antibodyECD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibodyECD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (C-Term) antibodyECD 适用: 人, 山羊, 马, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 72-121) antibodyECD 适用: 人, 山羊, 马, 兔, Cow, Pig, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
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别名
- ECD
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背景
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Synonyms: Protein ecdysoneless homolog|Human suppressor of GCR two (hSGT1)|ECD
Background: Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP(PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes(PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins(PubMed:19640839). The cell cycle-regulating function may depend on its RUVBL1-mediated association with the R2TP complex(PubMed:26711270). May play a role in regulation of pre-mRNA splicing(PubMed:24722212).
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分子量
- 70-100 kDa
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基因ID
- 11319
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UniProt
- O95905
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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