DBNL 抗体
Quick Overview for DBNL 抗体 (ABIN7113623)
抗原
See all DBNL 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DBNL antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- drebrin-like
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亚型
- IgG
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anti-Drebrin-Like (DBNL) (N-Term) antibody
DBNL 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin-Like (DBNL) (N-Term) antibodyVerified DBNL 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Drebrin-Like (DBNL) (AA 201-300) antibodyDBNL 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Drebrin-Like (DBNL) (AA 251-300) antibodyDBNL 适用: 人, 小鼠, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Drebrin-Like (DBNL) (AA 131-430) antibodyDBNL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DBNL (Drebrin-Like (DBNL))
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别名
- DBNL
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背景
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Synonyms: Drebrin-like protein|Cervical SH3P7|Cervical mucin-associated protein|Drebrin-F|HPK1-interacting protein of 55 kDa (HIP-55)|SH3 domain-containing protein 7|DBNL|CMAP|SH3P7
Background: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes(By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.
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分子量
- 55 kDa
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基因ID
- 28988
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UniProt
- Q9UJU6
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途径
- TCR Signaling, Regulation of Actin Filament Polymerization
抗原
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