DOC2B 抗体
Quick Overview for DOC2B 抗体 (ABIN7113615)
抗原
See all DOC2B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DOC2B antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- double C2-like domains, beta
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亚型
- IgG
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anti-Double C2-Like Domains, beta (DOC2B) (AA 1-412) antibody
DOC2B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Double C2-Like Domains, beta (DOC2B) (AA 7-180) antibodyDOC2B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Double C2-Like Domains, beta (DOC2B) antibodyDOC2B 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DOC2B (Double C2-Like Domains, beta (DOC2B))
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别名
- DOC2B
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背景
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Synonyms: Double C2-like domain-containing protein beta (Doc2-beta)|DOC2B|DOC2BL
Background: Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes(By similarity).
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分子量
- 46 kDa
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基因ID
- 8447
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UniProt
- Q14184
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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