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DNAJC10 抗体

DNAJC10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7113582
发货至: 中国
  • 抗原 See all DNAJC10 抗体
    DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
    适用
    • 26
    • 18
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 34
    • 4
    克隆类型
    • 35
    • 3
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This DNAJC10 antibody is un-conjugated
    应用范围
    • 23
    • 19
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    DnaJ(Hsp40) homolog, subfamily C, member 10
    亚型
    IgG
    Top Product
    Discover our top product DNAJC10 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
    别名
    DNAJC10 (DNAJC10 产品)
    别名
    ERdj5 antibody, JPDI antibody, MTHr antibody, PDIA19 antibody, 1200006L06Rik antibody, D2Ertd706e antibody, dnajc10 antibody, zgc:162218 antibody, DnaJ heat shock protein family (Hsp40) member C10 antibody, DnaJ (Hsp40) homolog, subfamily C, member 10 antibody, DNAJC10 antibody, Dnajc10 antibody, dnajc10 antibody
    背景
    Synonyms:ERDJ5 Background:Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation(ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
    分子量
    75-80 kDa
    基因ID
    54431
    UniProt
    Q8IXB1
    途径
    Cell RedoxHomeostasis
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