DNAJC10 抗体
Quick Overview for DNAJC10 抗体 (ABIN7113582)
抗原
See all DNAJC10 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DNAJC10 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- DnaJ(Hsp40) homolog, subfamily C, member 10
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亚型
- IgG
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anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) (AA 688-793) antibody
DNAJC10 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) (AA 688-793) antibodyDNAJC10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) (AA 614-793) antibodyDNAJC10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) (AA 521-793) antibodyDNAJC10 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) (AA 688-793) antibodyDNAJC10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) (C-Term) antibodyDNAJC10 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) (AA 35-84) antibodyDNAJC10 适用: 人, 小鼠, 大鼠, 兔, Cow, 斑马鱼, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10) (N-Term) antibodyDNAJC10 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 斑马鱼, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
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别名
- DNAJC10
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背景
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Synonyms: DnaJ homolog subfamily C member 10|Endoplasmic reticulum DNA J domain-containing protein 5 (ER-resident protein ERdj5, ERdj5)|Macrothioredoxin (MTHr)|DNAJC10|ERDJ5
Background: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation(ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
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分子量
- 75-80 kDa
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基因ID
- 54431
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UniProt
- Q8IXB1
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途径
- Cell RedoxHomeostasis
抗原
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