DNAJA1 抗体
Quick Overview for DNAJA1 抗体 (ABIN7113564)
抗原
See all DNAJA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DNAJA1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- DnaJ(Hsp40) homolog, subfamily A, member 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))
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别名
- DNAJA1
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背景
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Synonyms: DnaJ homolog subfamily A member 1|DnaJ protein homolog 2|HSDJ|Heat shock 40 kDa protein 4|Heat shock protein J2 (HSJ-2)|Human DnaJ protein 2 (hDj-2)|DNAJA1|DNAJ2|HDJ2|HSJ2|HSPF4
Background: Co-chaperone for HSPA8/Hsc70(PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A(in vitro)(PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis(PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV(PubMed:24512202).
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分子量
- 45 kDa
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基因ID
- 3301
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UniProt
- P31689
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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