DMAP1 抗体
Quick Overview for DMAP1 抗体 (ABIN7113552)
抗原
See all DMAP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DMAP1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- DNA methyltransferase 1 associated protein 1
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亚型
- IgG
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应用备注
- WB: 1:1000 - 1:4000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
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别名
- DMAP1
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背景
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Synonyms: DNA methyltransferase 1-associated protein 1 (DNMAP1, DNMT1-associated protein 1)|DMAP1|KIAA1425
Background: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
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分子量
- 60 kDa
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基因ID
- 55929
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UniProt
- Q9NPF5
抗原
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