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DMAP1 抗体

The 兔 多克隆 anti-DMAP1 antibody (ABIN7113552) specifically detects DMAP1 in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7113552
发货至: 中国
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Quick Overview for DMAP1 抗体 (ABIN7113552)

抗原

See all DMAP1 抗体
DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

适用

  • 48
  • 23
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  • 10
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人, 小鼠, 大鼠

宿主

  • 41
  • 4
  • 4

克隆类型

  • 33
  • 16
多克隆

标记

  • 31
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 1
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This DMAP1 antibody is un-conjugated

应用范围

  • 38
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  • 5
  • 2
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  • 2
  • 1
  • 1
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 原理

    DMAP1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    DNA methyltransferase 1 associated protein 1

    亚型

    IgG
  • 应用备注

    WB: 1:1000 - 1:4000, IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

    别名

    DMAP1

    背景

    Synonyms: DNA methyltransferase 1-associated protein 1 (DNMAP1, DNMT1-associated protein 1)|DMAP1|KIAA1425

    Background: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

    分子量

    60 kDa

    基因ID

    55929

    UniProt

    Q9NPF5
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