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DNMT3A 抗体

DNMT3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7113542
发货至: 中国
  • 抗原 See all DNMT3A 抗体
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    适用
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    人, 小鼠, 大鼠
    宿主
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    克隆类型
    • 106
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    多克隆
    标记
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    This DNMT3A antibody is un-conjugated
    应用范围
    • 94
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    DNA(cytosine-5-)-methyltransferase 3 alpha
    亚型
    IgG
    Top Product
    Discover our top product DNMT3A Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
    别名
    DNMT3A (DNMT3A 产品)
    别名
    DNMT3A antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MmuIIIA antibody, dnmt3a1 antibody, dnmt6 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3A antibody, DNA (cytosine-5-)-methyltransferase 3 alpha b antibody, DNMT3A antibody, Dnmt3a antibody, dnmt3a antibody, dnmt3ab antibody
    背景
    Synonyms: Background:Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3(H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
    基因ID
    1788
    UniProt
    Q9Y6K1
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